Primary Cns Lymphoma: Current Diagnosis and Management

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منابع مشابه

Guidelines on the diagnosis and management of adult patients with primary CNS lymphoma (PCNSL) and primary intra-ocular lymphoma (PIOL)

Disclaimer While the advice and information in these guidelines is believed to be true and accurate at the time of going to press, neither the authors, the British Society for Haematology nor the publishers accept any legal responsibility for the content of these guidelines.

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Current and Emerging Pharmacotherapies for Primary CNS Lymphoma

Primary central nervous system lymphoma (PCNSL) constitutes a rare group of extranodal non-Hodgkin's lymphoma (NHL) primarily of B cell origin. It occurs in both immuno-competent and immune-compromised patients. High dose m ethotrexate (HD-MTX) based chemotherapy is the standard therapy. Chemotherapy with whole brain radiation therapy (WBRT) improves response rates and survival compared with WB...

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Guidelines on the diagnosis and management of primary CNS and intra-ocular Lymphoma (PCNSL)

1. Unless clinically contra-indicated, such as in a patient of very poor performance status, diagnosis of PCNSL should always be confirmed histologically by image guided biopsy. Steroids are to be avoided pre surgery if at all possible 2. Staging should include measurement of serum LDH; CT scanning of chest, abdomen and pelvis; testicular ultrasonography in elderly males; lumbar puncture for CS...

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Posttransplant primary CNS lymphoma.

The records and neuro-imaging studies of 8 cases of posttransplant primary CNS lymphoma (PT-PCNSL) diagnosed at Mayo Clinic Rochester between 1970 and 1998 were reviewed retrospectively. All patients received organ transplantation. Patients who had hematologic transplantation were not included in the analysis. The median and mean age of the 4 men and 4 women was 45 years (range, 34 to 50 years)...

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Primary CNS Lymphoma

Primary diffuse large B-cell lymphoma (DLBCL) of the central nervous system is an aggressive malignancy that exhibits unique biological features and characteristic clinical behaviour, with overall long-term survival rates of around 20-40%. Clinical outcome has improved following the advent of chemoradiation protocols incorporating high-dose methotrexate in the mid-1980s, but disease relapse and...

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ژورنال

عنوان ژورنال: Journal of Cancer Prevention & Current Research

سال: 2016

ISSN: 2373-633X

DOI: 10.15406/jcpcr.2016.04.00117